At present, momentous changes unseen in a century are accelerating, and science and technology have become the key variable of global change. How to find solutions to the changes through scientific and technological innovation is a topic faced by every country and region, and also tests the wisdom of think tanks in all countries and territories. Science and technology think tanks thus move to the center of the ideas market stage.

　　In the face of great change, the book focuses on two core questions:

　　1. What are the world's leading science and technology think tanks working on?

　　2. What do the world's representative science and technology think tanks think about key science and technology issues?

　　For Question 1, the book selects 12 representative science and technology think tanks in the world, sorts out the thousands of published research results of these science and technology think tanks in the past five years, and tries to summarize the thought map, representative research problems and research trends of the current global science and technology think tanks.

　　For Question 2, the book selects 6 key science and technology issues: integrated circuit, artificial intelligence, biomedicine, co-opetition relationship in science and technology, climate change and innovation system, and aims to present the overall advisory suggestions of the global think tank community by analyzing the research of cutting-edge science and technology think tanks on the above issues.

　　Led by the Shanghai Institute for Science of Science, one of the earliest science and technology think tanks in China, more than 10 think tank researchers from different professional fields have been organized to deeply interpret the research and judgment of global science and technology innovation by global science and technology think tanks, and strive to predict the dynamics of science and technology strategies of major countries in the world, to provide strong intellectual support for scientific decision-making and promote the continuous development of science and technology.